Venom Encore
Guarantee Poisoned attacks, turn critical hits into darts and permanent Rupture, then multiply those status-fed hits with fast Strike triggers.
Gods

Lady Justice
Critical setup + safety
Merciful Attack
Guidance
Protection
Guidance supplies guaranteed critical attacks for Poison Darts and Open Wounds, while Merciful Attack adds Weakened for Dirty Tricks.

Krom
Rupturing Strikes
Shurikens
Hemorrhage
Shurikens and Chains of War add Strike damage and Rupture, which Hemorrhage turns into a second status-damage engine.

Leigong
Fast Strike triggers
Chain Lightning
Alacrity
Thunderstruck
Chain Lightning and Alacrity reward repeated Attack hits, while Thunderstruck improves post-dash Attack triggers.
Blessing Priorities
Core
4 blessingsMerciful Attack
Lady Justice · Attack
Your Attacks become stronger and apply Weakened .
Build role: Applies Weakened on Attack, activating Dirty Tricks while reducing affected enemies' damage.
Shurikens
Krom · Strike
Your Attack hits shoot out rupturing shurikens for each enemy hit.
Build role: Adds a reliable Attack-triggered Strike that applies Ruptured.
Chain Lightning
Leigong · Strike
Your Attack hits have a chance to cause a chain lightning.
Build role: Adds a Luck-scaled Strike trigger that spreads damage across packs.
Guidance
Lady Justice · Passive
Every few seconds, your next Attack is a certain critical hit.
Build role: Periodically guarantees a critical Attack, triggering Poison Darts and permanent Rupture together.
High Priority
4 blessingsHemorrhage
Krom · Passive
Legend
Rupture deals more damage for each consecutive instance of damage.
Build role: Improves consecutive Rupture damage from Shurikens, Chains of War, and Open Wounds.
Alacrity
Leigong · Passive
For each enemy you hit with your Attack , your Strike damage is increased temporarily.
Build role: Repeated Attack hits temporarily increase Strike Damage.
Thunderstruck
Leigong · Passive
After dashing, there is a chance you gain a status that gives you increased Attack chance triggers on your next Attack .
Build role: After dashing, improves the chance-based triggers attached to Nixi's next Attack.
Protection
Lady Justice · Passive
All damage dealt to you is reduced.
Build role: Reduces incoming damage while Nixi waits for Poison and Rupture to work.
Situational
3 blessingsChains of War
Krom · Strike
Your Attack hits have a chance to create a chain that rotates around you for a limited time, damaging, rupturing and knocking back enemies.
Build role: Use as an additional Strike when slot capacity permits; it damages, Ruptures, and controls nearby enemies.
Split-second Attack
Leigong · Attack
Your Attacks become stronger and have a chance to trigger an additional attack.
Build role: Replace Merciful Attack when extra attacks matter more than Weakened and defensive control.
Bloodlust
Krom · Passive
You gain attack speed for each ruptured enemy.
Build role: Adds Attack Speed when Rupture coverage is already consistent.
Gear Priorities
primary
Attack Damage
Scales normal attacks, Poison Darts, and Scorpion's Poison conversion.
Attack Critical Chance
Triggers Poison Darts and Open Wounds more consistently.
secondary
Luck
Improves chance-based blessing triggers such as Chain Lightning.
Strike Damage
Scales Shurikens, Chain Lightning, and optional Chains of War.
useful
Attack Speed
Creates more opportunities to apply Poison and trigger Strikes.
Talents
Envenom
Rank 5/5Your Attacks have a chance to apply Poisoned on attack.
Build impact: Raises the Attack chance to apply Poisoned to 100%.
Deep Poison
Rank 2/2Your Poisoned status effects now stack.
Build impact: Adds two Poison stacks so Scorpion and Crippling Dosage can build meaningful pressure.
Scorpion
Rank 3/3Your Poisoned status effects deal a percentage of your Attack Damage every second.
Build impact: Makes Poisoned deal 6% of Nixi's Attack Damage every second.
Poison Darts
Rank 3/3Your Attack Critical hits shoot out darts that apply Poisoned and deal a percentage of your Attack damage.
Build impact: Critical attacks fire four darts that apply Poisoned and deal 15% of Attack Damage.
Hidden Tools
Rank 3/3You shoot out more Poison Darts.
Build impact: Adds six Poison Darts, bringing each critical trigger to ten darts.
Dirty Tricks
Rank 4/4You deal more damage to enemies that have a Status applied to them.
Build impact: Adds +16% Damage against enemies carrying any status.
Precision Strikes
Rank 3/3Your Attacks have a chance to deal critical damage.
Build impact: Adds +3% Attack Critical Chance to start the dart and Rupture triggers.
Open Wounds
Rank 1/1Your attack critical hits apply permanent Rupture.
Build impact: Critical attacks add permanent Rupture, supplying another status for Dirty Tricks.
Crippling Dosage
Rank 3/3Poisoned enemies move and attack slower for each stack applied.
Build impact: Each Poison stack slows enemy movement and attacks by 6%.
Daggerstorm
Rank 2/3Your attacks have a chance to trigger an additional attack.
Build impact: Gives attacks a 16% chance to trigger an additional attack.
Lethality
Rank 2/3Whenever you hit an enemy, your Prime Critical Chance is increased temporarily.
Build impact: Attack hits briefly build Prime Critical Chance, helping the critical-hit engine.
Assassination
Rank 2/5You deal more damage to elites and bosses.
Build impact: Adds +20% Damage against elites and bosses.
A Thousand Cuts
Rank 1/1Your Strikes deal more damage to nearby enemies.
Build impact: Completes the Scorpion branch; the extracted rank data records two additional Poison stacks.
Talent Tree
Sharpened Blades
Rank 0 / 3Your Attack Damage is increased.
- Attack Damage: +2%
Underworld Savvy
Rank 2 / 5Your Strikes deal more damage.
- Strike Damage: +2%
Precision Strikes
Rank 3 / 3Your Attacks have a chance to deal critical damage.
- Attack Critical Chance: +3%
Trickster’s Prescience
Rank 0 / 2You gain more control over your god offers.
- Alterations: +2
Shadowshift
Rank 0 / 3Whenever you dash through an enemy, enter Shadowshift for a limited duration. If you attack, leave Shadowshift and lose all dash charges. Your attack is a guaranteed critical hit and has increased Attack Damage for each dash charge spent.
- Shadowshift: Duration: +2.5s
- Shadowshift: Cooldown: +6s
- Shadowshift: Attack Damage per Charge: +166%
Dexterity
Rank 0 / 3Your Attack Speed is increased.
- Attack Speed: +2%
Open Wounds
Rank 1 / 1Your attack critical hits apply permanent Rupture.
Envenom
Rank 5 / 5Your Attacks have a chance to apply Poisoned on attack.
- Envenom: Chance: +100%
Reclusive Warp
Rank 0 / 3Your experience pull area is increased.
- Pull Area: +20%
Dirty Tricks
Rank 4 / 4You deal more damage to enemies that have a Status applied to them.
- Damage: +16%
Greed is Good
Rank 0 / 2Whenever you pick up gold, your Attack Speed is increased until your next attack.
- Next Attack Speed: +50%
Fleet Footed
Rank 0 / 4You move faster.
- Movement Speed: +3%
Dark Alley
Rank 0 / 2When you leave Shadowshift, there is a chance you recharge a dash.
- Dark Alley: Chance: +50%
Lethality
Rank 2 / 3Whenever you hit an enemy, your Prime Critical Chance is increased temporarily.
- Lethality: Prime Critical Chance: +1%
- Lethality: Duration: +0.3s
Cutpurse
Rank 0 / 3Whenever you hit an enemy, there is a chance it spawns gold behind it.
- Cutpurse: Chance: +2%
Crippling Dosage
Rank 3 / 3Poisoned enemies move and attack slower for each stack applied.
- Slow: -6%
Makeshift Combat
Rank 0 / 1You have more Strike, Cast and Power slots.
- Strike Slots: +1
- Cast Slots: +1
- Power Slots: +1
Cloak and Dagger
Rank 0 / 4While in Shadowshift, your Evasion and Prime Damage are increased.
- Prime Damage in Shadowshift: +10%
- Evasion in Shadowshift: +20%
Eviscerate
Rank 0 / 3You gain additional Attack and Strike Damage bonuses from items.
- Percentage: +6%
Poison Darts
Rank 3 / 3Your Attack Critical hits shoot out darts that apply Poisoned and deal a percentage of your Attack damage.
- Poison Darts: Darts: +4
- Poison Darts: Attack Damage: +15%
Deep Poison
Rank 2 / 2Your Poisoned status effects now stack.
- Poison Stacks: +2
Fight or Flight
Rank 0 / 3Your attack hits have a chance to recharge a dash.
- Fight or Flight: Chance: +11%
Swerving Darkness
Rank 0 / 4While in Shadowshift, your Dash Recharge Speed is increased and your Dash Distance is reduced.
- Recharge Speed in Shadowshift: +150%
- Dash Distance in Shadowshift: -50%
Assassination
Rank 2 / 5You deal more damage to elites and bosses.
- Damage vs Elites and Bosses: +20%
Go Again
Rank 0 / 3Whenever you end a dash, gain increased Dash Damage temporarily.
- Go Again: Dash Damage: +66%
- Go Again: Duration: +0.2s
Dance of Shadows
Rank 0 / 3While dashing in Shadowshift, you perform shadow attacks towards nearby enemies.
- Dance of Shadows: Attack Rate: +0.36
Cold Blood
Rank 0 / 3Your Strike Damage is increased, but you have less life.
- Strike Damage: +10%
- Life: -5%
Rogue's Legacy
Rank 0 / 3Your Attack Damage is increased for each empty Strike slot you have.
- Rogue's Legacy: Attack Damage: +4%
Scorpion
Rank 3 / 3Your Poisoned status effects deal a percentage of your Attack Damage every second.
- Scorpion: Percentage: +6%
Daggerstorm
Rank 2 / 3Your attacks have a chance to trigger an additional attack.
- Daggerstorm: Chance: +16%
Endless Night
Rank 0 / 1When you leave Shadowshift there is a chance you enter it again, but your Shadowshift cooldown is increased.
- Cooldown: +4s
- Endless Night: Chance: +66%
Vendetta
Rank 0 / 1Your Critical hits deal extra damage.
- Critical Damage: +300%
A Thousand Cuts
Rank 1 / 1Your Strikes deal more damage to nearby enemies.
- Poison Stacks: +2
Finesse
Rank 0 / 1You gain more dash charges.
- Dash Charges: +1
Alternatives
Blessing-slot context
Nixi's base slot counts are missing from the current hero source. Start with Shurikens and add Chain Lightning only when the available Strike capacity allows it.
No Lady Justice?
Use Summer for Searing Attack and Fury. Burning still activates Dirty Tricks, but you lose guaranteed critical setup from Guidance.
No Krom?
Use Winter for Ice Shards and Icebound. Poisoned enemies gain a control package instead of stronger Rupture.
Aggressive Attack swap
Take Split-second Attack instead of Merciful Attack when survival is comfortable and extra attacks outweigh Weakened.